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Penicillin Pediatric Dose Calculator

Harriet Lane–based dosing records for Penicillin. Use with patient weight, indication, and local antimicrobial stewardship policy.

Search full dosage browser for Penicillin

Aztreonam

Generic: Aztreonam

Indication: Gramnegative infections including in patients with immediate hypersensitivity to penicillins/cephalosporins; limited activity vs Pseudomonas depending on susceptibility; no activity vs grampositives or anaerobes.

Pediatric dosage: 30-50 mg/kg/dose IV every 6-8 hr (maximum 2 g/dose).

Route: IV

Frequency: Every 6-8 hr.

Warnings: Hypersensitivity (rare crossreactivity with other betalactams); adjust for renal impairment.

Penicillin G (Aqueous)

Generic: Pfizerpen

Indication: Serious infections due to susceptible organisms

Pediatric dosage: 100,000-400,000 units/kg/day divided q4-6hr

Route: IV/IM

Frequency: Every 4-6 hours

Penicillin G Benzathine

Generic: Bicillin L-A

Indication: Syphilis; Rheumatic fever prophylaxis

Pediatric dosage: Syphilis: 50,000 units/kg single dose

Route: IM

Frequency: Single dose or monthly

Penicillin G Procaine

Generic: Wycillin

Indication: Moderately severe infections

Pediatric dosage: 50,000 units/kg/day

Route: IM

Frequency: Once or twice daily

Penicillin V Potassium

Generic: Veetids, Pen-Vee K

Indication: Mild to moderate infections (strep pharyngitis

Pediatric dosage: 250-500 mg q6-8hr

Route: 25-50 mg/kg/day divided q6-8hr

Frequency: Oral

Probenecid

Generic: Benemid

Indication: Gout (hyperuricemia); To increase penicillin levels

Pediatric dosage: Various generics Penicillin therapy adjuvant, uric acidelowering Tabs: 500 mg To prolong penicillin levels. Child (2e14 yr): 25 mg/kg PO x 1, then 40 mg mg/dose. Use adult dose if >50 kg. Adult: 500 mg PO QID Hyperuricemia with gout: Adult: 250 mg PO BID x 1 wk, then 500 mg PO B up to a max. dose of 2e3 g/24 hr O BID Gonorrhea, antibiotic adjunct (administer just prio <=45 kg: 23 mg/kg/dose PO x 1 >45 kg: 1 g PO x 1 Prevention of nephrotoxicity from cidofovir: See C Use with caution in patients with peptic ulcer dise <2 yr and patients with renal insufficiency. Do n D 2 Yes Yes No tiate therapy at the lower dosage range >=8 Yr and Adult 100e125 mg PO QHS 100e125 mg PO BID 100e125 mg PO TID ID or 250 mg PO TID-QID; 24 hr O TIDdQID max. dose: 2 g/24 hr pulmonary insufficiency. Primidone is drug interactions and toxicities cause vertigo, nausea, leukopenia, malignant nd systemic lupus-like syndrome. Monitor for decrease primidone absorption. Adjust dose in herapeutic levels: 5e12 mg/L of commended serum sampling time at steady state: next scheduled dose after 1e4 days of continuous agent B ? Yes No No g/kg/24 hr O QID; max. single dose: 500 BID; may increase by 500 mg increments Q4 wk PRN or to antibiotic):

Route: Oral

Frequency: Two to four times daily

Penicillin V (Phenoxymethylpenicillin)

Generic: Penicillin V

Indication: Streptococcal pharyngitis and other susceptible infections.

Pediatric dosage: 25-50 mg/kg/day PO divided every 6-8 hr (max 3 g/day).

Route: PO

Frequency: Every 6-8 hr.

Warnings: Hypersensitivity reactions.

Benzathine Penicillin G

Generic: Benzathine penicillin G

Indication: Streptococcal pharyngitis; rheumatic fever prophylaxis; yaws/treponematoses.

Pediatric dosage: Strep pharyngitis: <27 kg: 600,000 units IM once >=27 kg: 1.2 million units IM once. Rheumatic fever prophylaxis: 1.2 million units IM every 3-4 weeks.

Route: IM

Frequency: Single dose (treatment) or every 3-4 weeks (prophylaxis).

Warnings: Injection pain; hypersensitivity including anaphylaxis.