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Ampicillin Pediatric Dose Calculator

Harriet Lane–based dosing records for Ampicillin. Use with patient weight, indication, and local antimicrobial stewardship policy.

Search full dosage browser for Ampicillin

Ampicillin

Generic: Principen

Indication: Gram-positive and some gram-negative infections; meningitis (neonatal), respiratory, GI, GU infections.

Pediatric dosage: Neonates <7 days: 50 mg/kg IV every 12 hours >7 days: 50 mg/kg IV every 8 hours. Children: 25-50 mg/kg/dose every 6 hours (max 2 g/dose).

Route: PO, IV, IM

Frequency: Every 4-6 hours (depending on age and infection site).

Warnings: Allergic reactions common in penicillin-allergic patients; adjust dose in renal impairment.

Ampicillin + Sulbactam

Generic: Unasyn

Indication: Gram-positive and some gram-negative infections; meningitis (neonatal), respiratory, GI, GU infections.

Pediatric dosage: Neonates <7 days: 50 mg/kg IV every 12 hours >7 days: 50 mg/kg IV every 8 hours. Children: 25-50 mg/kg/dose every 6 hours (max 2 g/dose).

Route: PO, IV, IM

Frequency: Every 4-6 hours (depending on age and infection site).

Warnings: Allergic reactions common in penicillin-allergic patients; adjust dose in renal impairment.

Sulbactam

Generic: Component of Unasyn

Indication: Used in combination with ampicillin

Pediatric dosage: Varies

Route: IV/IM

Frequency: Varies