Acyclovir Pediatric Dose Calculator

Acyclovir

Generic: Zovirax

Indication: HSV (Mucocutaneous, Encephalitis, Neonatal), VZV (Chickenpox, Zoster)

Pediatric dosage: Neonatal HSV (Birth-3 mo): IV: 20 mg/kg/dose every 8 hours for 14 days (SEM) or 21 days (CNS/Disseminated). HSV Encephalitis (3 mo - 12 yr): IV: 20 mg/kg/dose every 8 hours for 14-21 days. HSV Encephalitis (>12 yr): IV: 10 mg/kg/dose every 8 hours for 14-21 days. Mucocutaneous HSV (Immunocompromised): IV: 10 mg/kg/dose every 8 hours for 7-14 days. PO: 10-20 mg/kg/dose (max 400 mg) 4 times daily. Varicella (Chickenpox) - Immunocompetent: PO: 20 mg/kg/dose (max 800 mg) 4 times daily for 5 days. Start within 24h of rash. Zoster (Shingles) - Immunocompetent: PO: 20 mg/kg/dose (max 800 mg) 5 times daily for 7-10 days.

Route: PO, IV, Topical

Frequency: Oral: 3-5 times daily; IV: Every 8 hours

Warnings: Renal impairment (adjust dose). Maintain adequate hydration to prevent crystalluria.

Foscarnet

Generic: Foscavir

Indication: CMV retinitis; Acyclovir-resistant HSV infections

Pediatric dosage: Foscavir and generics Antiviral agent Injection: 24 mg/mL (250 mL); preservative free Contains 10 mEq Na/g drug HIV positive or exposed with the following infectio CMV disease: Infant, child, and adolescent: Induction: 180 mg/kg/24 hr O Q8e12 hr i symptom improvement and convert to ma Maintenance: 90e120 mg/kg/dose Q24 hr CMV retinitis (disseminated disease; IV): Infant and child: Induction: 180 mg/kg/24 hr O Q8e12 hr x Maintenance: 90e120 mg/kg/24 hr once da Adolescent and adult: Induction: 180 mg/kg/24 hr O Q8e12 hr x Maintenance: 90e120 mg/kg/24 hr once da Acyclovir-resistant herpes simplex (limited data Infant and child: 40 mg/kg/dose Q8 hr or 60 mg Adolescent and adult: 40 mg/kg/dose Q8e12 Varicella zoster unresponsive to acyclovir (IV): Infant and child: 40e60 mg/kg/dose Q8 hr x Adolescent: 90 mg/kg/dose Q12 hr Varicella zoster, progressive outer retinal necro Infant, child, and adolescent: 90 mg/kg/dose intravitreal foscarnet with or without gancicl Intravitreal route for progressive outer retinal n Child and adolescent: 1.2 mg/0.05 mL or 2.4 m with IV foscarnet and ganciclovir and/or intr Use with caution in patients with renal insufficienc content). Discontinue use in adults if serum Cr >= (see Chapter 31). scheduled dose 12 hr from last dose nase. Safety and efficacy in pediatrics ypersensitivity to any components or other include headache, nausea, and dizziness. (use with caution in renal failure) and removed by (77 F); vial can be liquefied by running it are not affected). All doses must be diluted with at ation. DO NOT use polycarbonate syringe or or administering this medication. C 3 Yes No No on (IV): in combination with ganciclovir; continue until aintenance therapy x 14e21 days with or without ganciclovir aily x 14e21 days aily a; IV): g/kg/dose Q12 hr for up to 3 wk or until lesions heal hr x 14e21 days or until lesions heal x 7e10 days osis (IV): Q12 hr in combination with ganciclovir IV and lovir necrosis (HIV positive or exposed): mg/0.1 mL per dose 2e3 times weekly in combination ravitreal ganciclovir cy and hypernatremia (large sodium >=2.9 mg/dL. Adjust dose in renal failure

Route: IV

Frequency: Varies

Valacyclovir

Generic: Valtrex

Indication: Herpes zoster (shingles); Genital herpes; Herpes labialis

Pediatric dosage: and child: 20 mg/kg/dose (max. 800 m

Route: Oral

Frequency: Varies